Yu H,† Zeng J,† Li Y, Thon V, Shi B, *Chen X. Effective one-pot multienzyme (OPME) synthesis of monotreme milk oligosaccharides (MOSs) and other sialosides containing a 4-O-acetyl sialic acid. †These authors contributed equally. Biomol. Chem. 2016, 14, 8586-8597. PMID: 27548611. PMCID: PMC5036589. DOI: 10.1039/C6OB01706A.

Zhao C, Wu Y, Yu H, Shah IM, Li Y, Zeng J, Liu B, Mills DA, *Chen X. The one-pot multienzyme (OPME) synthesis of human blood group H antigens and a human milk oligosaccharide (HMOS) with highly active Thermosynechococcus elongatus a1–2-fucosyltransferase. Chem. Commun. 2016, 52, 3899–3902. PMID: 26864394. PMCID: PMC4775349. DOI: 10.1039/C5CC10646J.

Yu H, Lau K, Thon V, Autran CA, Jantscher-Krenn E, Xue M, Li Y, Sugiarto G, Qu J, Mu S, Ding L, Bode L, *Chen X. Synthetic disialyl hexasaccharides protect neonatal rats from necrotizing enterocolitis. Angew. Chem. Int. Ed. 2014, 53, 6687-6691. PMID: 24848971. PMCID: PMC4147952. DOI: 10.1002/anie.201403588.

 

Reviews

*Chen X. Human milk oligosaccharides (HMOS): Structure, function, and enzyme-catalyzed synthesis. In Advances in Carbohydrate Chemistry and Biochemistry David C. Baker, Derek Horton, Eds. Academic Press, ACCB, UK, 2015, 72, 113-190. PMID: 26613816. DOI: 10.1016/bs.accb.2015.08.002.