An got his B.S. and M.S. degrees in pharmaceutical science at Perking University, where he worked with Professor Xin-Shan Ye on the synthesis of sialylated glycopeptides as anti-tumor vaccines. He joined the Chen lab in the winter of 2014 and now he is a Ph.D. candidate in chemistry. His research interests are the enzymatic synthesis of sialidase inhibitors, and the enzymatic synthesis of sialosides containing N-acetylated sialic acids as stable mimics of the natural occurring O-acetylated sialic acids.
1. Huo, C.-X.; Zheng, X.-J.; Xiao, A.; Liu, C.-C.; Sun, S.; Lv, Z.; *Ye, X.-S. Synthetic and immunological studies of N-acyl modified S-linked STn derivatives as anticancer vaccine candidates. Org. Biomol. Chem. 2015, 13, 3677-3690.
2. Xiao, A.; Zheng, X.-J.; Song, C.; Gui, Y.; Huo, C.-X.; *Ye, X.-S.; Synthesis and immunological evaluation of MUC1 glycopeptide conjugates bearing N-acetyl modified STn derivatives as anticancer vaccines. Org. Biomol. Chem. 2016, 14, 7226-7237.
3. Khedri, Z.;† Xiao, A.;† Yu, H.;† Landig, C. S.; Li, W.; Diaz, S.; Wasik, B. R.; Parrish, C. R.; Wang, L.-P.; *Varki, A.; *Chen, X. A Chemical Biology Solution to Problems with Studying Biologically Important but Unstable 9-O- Acetyl Sialic Acids. †These authors contributed equally. ACS Chem. Biol. 2017, 12, 214–224.